兔抗ATP6V1D多克隆抗体

Background:

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes the V1 domain D subunit protein.

Applications:

ELISA, WB, IHC

Name of antibody:

ATP6V1D

Immunogen:

Fusion protein of human ATP6V1D

Full name:

ATPase H+ transporting V1 subunit D

Synonyms:

VATD; VMA8; ATP6M

SwissProt:

Q9Y5K8

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer and Human colorectal cancer

IHC Recommend dilution:

100-300

WB Predicted band size:

28 kDa

WB Positive control:

Human fetal brain tissue lysate

WB Recommended dilution:

500-2000