兔抗ATG4A多克隆抗体

Background:

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified.

Applications:

ELISA, WB, IHC

Name of antibody:

ATG4A

Immunogen:

Synthetic peptide of human ATG4A

Full name:

autophagy related 4A, cysteine peptidase

Synonyms：

APG4A; AUTL2

SwissProt:

Q8WYN0

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer and Human brain

IHC Recommend dilution:

25-100

WB Predicted band size:

45 kDa

WB Positive control:

231 cells and human liver cancer tissue

WB Recommended dilution:

200-1000