兔抗ARPC1B多克隆抗体

Background:

This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase.

Applications:

ELISA, WB, IHC

Name of antibody:

ARPC1B

Immunogen:

Fusion protein of human ARPC1B

Full name:

actin related protein 2/3 complex subunit 1B

Synonyms:

ARC41; PLTEID; p40-ARC; p41-ARC

SwissProt:

O15143

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human breast cancer

IHC Recommend dilution:

50-100

WB Predicted band size:

41 kDa

WB Positive control:

Hela cell lysate

WB Recommended dilution:

500-2000