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021-54845833/15800441009
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Background: |
Eukaryotic translation initiation factor 3 subunit H is a protein that in humans is encoded by the EIF3H gene. Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP: methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
EIF3H |
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Immunogen: |
Fusion protein of human EIF3H |
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Full name: |
eukaryotic translation initiation factor 3, subunit H |
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Synonyms： |
EIF3S3; eIF3-p40; eIF3-gamma |
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SwissProt: |
O15372 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human colon cancer and human brain |
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IHC Recommend dilution: |
50-200 |
