兔抗USP14多克隆抗体

Background:

This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Applications:

ELISA, WB

Name of antibody:

USP14

Immunogen:

Fusion protein of human USP14

Full name:

ubiquitin specific peptidase 14

Synonyms:

TGT

SwissProt:

P54578

ELISA Recommended dilution:

5000-10000

WB Predicted band size:

56 kDa

WB Positive control:

A172 and Jurkat cell lysates

WB Recommended dilution:

500-2000