兔抗CD63多克隆抗体

Background:

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms.

Applications:

ELISA, WB

Name of antibody:

CD63

Immunogen:

Synthetic peptide of human CD63

Full name:

CD63 molecule

Synonyms:

MLA1; ME491; LAMP-3; OMA81H; TSPAN30

SwissProt:

P08962

ELISA Recommended dilution:

5000-10000

WB Predicted band size:

26 kDa

WB Positive control:

293T and A549 cell lysates

WB Recommended dilution:

500-2000