兔抗NTRK2(Phospho-Tyr706Tyr707)多克隆抗体

Background:

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.

Applications:

IHC

Name of antibody:

NTRK2(Phospho-Tyr706/Tyr707)

Immunogen:

Peptide sequence around phosphorylation site of tyrosine 706/tyrosine 707 (T-D-Y(p)-Y(p)-R-V)derived from Human Trk B.

Full name:

neurotrophic tyrosine kinase, receptor, type 2

Synonyms：

TRKB; trk-B; GP145-TrkB

SwissProt:

Q16620

IHC positive control:

Human brain tissue

IHC Recommend dilution:

50-100