兔抗FOXO4 (Phospho-Ser197)多克隆抗体

Background:

Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle.

Applications:

WB, IHC, IF

Name of antibody:

FOXO4 (Phospho-Ser197)

Immunogen:

Synthetic peptide of human FOXO4 (Phospho-Ser197)

Full name:

forkhead box O4 (Phospho-Ser197)

Synonyms：

AFX; AFX1; MLLT7

SwissProt:

P98177

IHC positive control:

Human breast carcinoma

IHC Recommend dilution:

50-100

WB Predicted band size:

54 kDa

WB Positive control:

293 cells untreated or treated with serum

WB Recommended dilution:

500-1000

IF Positive control:

MCF7 cells

IF Recommended dilution

100-200