兔抗CDH11多克隆抗体

Background:

This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.

Applications:

WB

Name of antibody:

CDH11

Immunogen:

Synthesized peptide derived from internal of human CDH11.

Full name:

cadherin 11, type 2, OB-cadherin (osteoblast)

Synonyms：

OB; CAD11; CDHOB; OSF-4

SwissProt:

P55287

WB Predicted band size:

88 kDa

WB Positive control:

Jurkat cells lysate

WB Recommended dilution:

500-3000