中文名称:兔抗SLC4A4多克隆抗体
别 名: KNBC; NBC1; NBC2; pNBC; HNBC1; hhNMC; SLC4A5; NBCe1-A
抗 原: SLC4A4
储 存: 冷冻(-20℃)
宿 主: Rabbit
相关类别: 一抗
反应种属: Human, Mouse, Rat
标记物: Unconjugate
克隆类型: rabbit polyclonal
技术规格
Background: |
This gene encodes a sodium bicarbonate cotransporter (NBC) involved in the regulation of bicarbonate secretion and absorption and intracellular pH. Mutations in this gene are associated with proximal renal tubular acidosis. Multiple transcript variants encoding different isoforms have been found for this gene. Sodium bicarbonate cotransporters (NBCs) mediate the coupled movement of sodium and bicarbonate ions across the plasma membrane of many cells. This is an electrogenic process with an apparent stoichiometry of 3 bicarbonate ions per sodium ion. Sodium bicarbonate cotransport is involved in bicarbonate secretion/absorption and intracellular pH regulation. Romero and Boron (1999) reviewed NBCs. Soleimani and Burnham (2000) reviewed NBCs and their regulation in physiologic and pathophysiologic states. |
Applications: |
ELISA, IHC |
Name of antibody: |
SLC4A4 |
Immunogen: |
Fusion protein of human SLC4A4 |
Full name: |
solute carrier family 4, sodium bicarbonate cotransporter, member 4 |
Synonyms: |
KNBC; NBC1; NBC2; pNBC; HNBC1; hhNMC; SLC4A5; NBCe1-A |
SwissProt: |
Q9Y6R1 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human brain and human colon cancer |
IHC Recommend dilution: |
50-200 |