兔抗NOL3多克隆抗体

Background:

This gene encodes an anti-apoptotic protein that has been shown to down-regulate the enzyme activities of caspase 2, caspase 8 and tumor protein p53. Multiple transcript variants encoding different isoforms have been found for this gene. Arc has been shown to localize to the cytoskeleton of neuronal cells and appears to colocalize with F-Actin, although it may associate with an Actin-associated protein rather than directly with F-Actin. It has been shown that cocaine-stimulated neuronal activity results in increased Arc mRNA levels in striatum.

Applications:

ELISA, IHC

Name of antibody:

NOL3

Immunogen:

Fusion protein of human NOL3

Full name:

nucleolar protein 3 (apoptosis repressor with CARD domain)

Synonyms：

ARC; FCM; MYP; NOP; NOP30

SwissProt:

O60936

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human brain and Huma