兔抗ACMSD多克隆抗体

Background:

The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.

Applications:

ELISA, IHC

Name of antibody:

ACMSD

Immunogen:

Fusion protein of human ACMSD

Full name:

aminocarboxymuconate semialdehyde decarboxylase

SwissProt:

Q8TDX5

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human colon cancer

IHC Recommend dilution:

15-50