兔抗ABCG2多克隆抗体

Background:

Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.

Applications:

WB

Name of antibody:

ABCG2

Immunogen:

Synthetic peptide of human ABCG2

Full name:

ATP-binding cassette, sub-family G (WHITE), member 2

Synonyms：

MRX; MXR; ABCP; BCRP; BMDP; MXR1; ABC15; BCRP1; CD338; GOUT1; CDw338; UAQTL1; EST157481

SwissProt:

Q9UNQ0

WB Predicted band size:

72 kDa

WB Positive control:

HL60 cells

WB Recommended dilution:

500-1000