兔抗UBR5多克隆抗体

Background:

This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation.

Applications:

WB, IHC

Name of antibody:

UBR5

Immunogen:

Synthesized peptide derived from Internal of human EDD.

Full name:

ubiquitin protein ligase E3 component n-recognin 5

Synonyms：

DD5; EDD; HYD; EDD1

SwissProt:

O95071

IHC positive control:

Human breast carcinoma tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

309 kDa

WB Positive control:

A549 cells lysate

WB Recommended dilution:

500-3000