兔抗CACNA1G多克隆抗体

Background:

Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas, the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1A subunit, which is predominantly expressed in neuronal tissue. Mutations in this gene are associated with 2 neurologic disorders, familial hemiplegic migraine and episodic ataxia 2.

Applications:

ELISA, IHC

Name of antibody:

CACNA1G

Immunogen:

Synthetic peptide of human CACNA1G

Full name:

calcium channel, voltage-dependent, T type, alpha 1G subunit

Synonyms：

NBR13; Cav3.1; Ca(V)T.1

SwissProt:

O43497

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human thyroid cancer and Human liver cancer

IHC Recommend dilution:

15-50