兔抗F2多克隆抗体

Background:

Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Finally, peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia.

Applications:

ELISA, IHC

Name of antibody:

F2

Immunogen:

Synthetic peptide of humanF2

Full name:

coagulation factor II (thrombin)

Synonyms：

PT; THPH1; RPRGL2

SwissProt:

P00734

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human thyroid cancer and Human prostate cancer

IHC Recommend dilution:

25-100