兔抗ERCC5多克隆抗体

Background:

This gene encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure.

Applications:

WB

Name of antibody:

ERCC5

Immunogen:

Synthesized peptide derived from internal of human ERCC5.

Full name:

excision repair cross-complementation group 5

Synonyms：

XPG; UVDR; XPGC; COFS3; ERCM2; ERCC5-201

SwissProt:

P28715

WB Predicted band size:

133 kDa

WB Positive control:

COLO cell lysate

WB Recommended dilution:

500-3000