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Background: |
This gene encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. |
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Applications: |
WB |
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Name of antibody: |
ERCC5 |
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Immunogen: |
Synthesized peptide derived from internal of human ERCC5. |
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Full name: |
excision repair cross-complementation group 5 |
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Synonyms： |
XPG; UVDR; XPGC; COFS3; ERCM2; ERCC5-201 |
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SwissProt: |
P28715 |
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WB Predicted band size: |
133 kDa |
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WB Positive control: |
COLO cell lysate |
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WB Recommended dilution: |
500-3000 |
