兔抗ESR1(Phospho-Tyr537) 多克隆抗体

Background:

This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone.

Applications:

WB, IHC

Name of antibody:

ESR1(Phospho-Tyr537)

Immunogen:

Peptide sequence around phosphorylation site of tyrosine 537(P-L-Y(p)-D-L) derived from Human Estrogen Receptor-α.

Full name:

estrogen receptor 1

Synonyms：

ER; ESR; Era; ESRA; ESTRR; NR3A1

SwissProt:

P03372

IHC positive control:

Human lung carcinoma tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

66 kDa

WB Positive control:

K562 cells lysates

WB Recommended dilution:

500-1000