兔抗JUP多克隆抗体

Background:

This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described.

Applications:

ELISA, WB, IHC

Name of antibody:

JUP

Immunogen:

Fusion protein of human JUP

Full name:

junction plakoglobin

Synonyms：

DP3; PDGB; PKGB; CTNNG; DPIII; ARVD12

SwissProt:

P14923

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human cervical cancer and Human lung cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

82 kDa

WB Positive control:

Mouse heart tissue and Hela cells, HUVEC cells and mouse skin tissue

WB Recommended dilution:

1000-5000