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Full name: |
serpin peptidase inhibitor, clade B (ovalbumin), member 1 |
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Synonyms: |
EI; LEI; PI2; MNEI; PI-2; HEL57; M/NEI; ELANH2 |
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Swissprot: |
P30740 |
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Gene Accession: |
BC009015 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene is a member of the serpin family of proteinase inhibitors. Members of this family maintain homeostasis by neutralizing overexpressed proteinase activity through their function as suicide substrates. This protein inhibits the neutrophil-derived proteinases neutrophil elastase, cathepsin G, and proteinase-3 and thus protects tissues from damage at inflammatory sites. Alternative splicing results in multiple transcript variants. |
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