概 述
| Full name: | transforming growth factor beta regulator 1 | 
| Synonyms: | NIAM; TB-5 | 
| Swissprot: | Q3YBR2 | 
| Gene Accession: | BC032312 | 
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE | 
| Expression system: | Escherichia coli | 
| Tags: | His tag C-Terminus, GST tag N-Terminus | 
| Background: | Acts as a growth inhibitor. Can activate p53/TP53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis. Redistributes CDKN2A into the nucleoplasm. Involved in maintaining chromosomal stability. | 
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