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中文名称：ACE2 抗原（重组蛋白）
英文名称： ACE2 Antigen (Recombinant Protein)
别 名： angiotensin I converting enzyme (peptidyl-dipeptidase A) 2; ACEH
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 556-740 amino acids of human ACE2 |
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Full name: |
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 |
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Synonyms: |
ACEH |
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Swissprot: |
Q9BYF1 |
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Gene Accession: |
BC039902 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63 |
