兔抗EPS15(Phospho-Tyr849) 多克隆抗体

Background:

This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2009]

Applications:

WB

Name of antibody:

EPS15(Phospho-Tyr849)

Immunogen:

Peptide sequence around phosphorylation site of tyrosine 849 (S-A-Y(p)-P-S) derived from Human Ephrin EPS15.

Full name:

epidermal growth factor receptor pathway substrate 15

Synonyms：

AF1P; AF-1P; MLLT5

SwissProt:

P42566

WB Predicted band size:

99 kDa

WB Positive control:

Jurkat cells lysates

WB Recommended dilution:

500-1000