兔抗EIF4G1多克隆抗体

Background:

The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage.

Applications:

ELISA, WB, IHC

Name of antibody:

EIF4G1

Immunogen:

Synthetic peptide of human EIF4G1

Full name:

eukaryotic translation initiation factor 4 gamma, 1

Synonyms：

P220; EIF4F; EIF4G; EIF4GI; PARK18; EIF-4G1

SwissProt:

Q04637

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human thyroid cancer and Human gastric cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

175 kDa

WB Positive control:

Lovo and 293T cells

WB Recommended dilution:

500-2000