兔抗EIF2AK2 (Phospho-Thr446) 多克隆抗体

Background:

Following activation by double-stranded RNA in the presence of ATP, the kinase becomes autophosphorylated and can catalyze the phosphorylation of the translation initiation factor EIF2S1, which leads to an inhibition of the initiation of protein synthesis. Double-stranded RNA is generated during the course of a viral infection.

Applications:

WB, IHC, IF

Name of antibody:

EIF2AK2 (Phospho-Thr446)

Immunogen:

Synthetic peptide of human EIF2AK2 (Phospho-Thr446)

Full name:

eukaryotic translation initiation factor 2-alpha kinase 2 (Phospho-Thr446)

Synonyms：

PKR; PRKR; EIF2AK1

SwissProt:

P19525

IHC positive control:

Human colon carcinoma

IHC Recommend dilution:

50-100

WB Predicted band size:

62 kDa

WB Positive control:

K562 cells

WB Recommended dilution:

500-1000

IF Positive control:

Hela cells

IF Recommended dilution

100-200