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Background: |
This gene encodes a member of the ephrin family. The protein is composed of a signal sequence, a receptor-binding region, a spacer region, and a hydrophobic region. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Posttranslational modifications determine whether this protein localizes to the nucleus or the cytoplasm. |
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Applications: |
ELISA, WB |
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Name of antibody: |
EFNA2 |
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Immunogen: |
Synthetic peptide of human EFNA2 |
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Full name: |
ephrin A2 |
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Synonyms: |
ELF-1; EPLG6; LERK6; HEK7-L; LERK-6 |
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SwissProt: |
O43921 |
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ELISA Recommended dilution: |
5000-10000 |
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WB Predicted band size: |
24 kDa |
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WB Positive control: |
231 cell lysate |
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WB Recommended dilution: |
200-1000 |
