兔抗DMGDH多克隆抗体

Background:

This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, WB

Name of antibody:

DMGDH

Immunogen:

Synthetic peptide of human DMGDH

Full name:

dimethylglycine dehydrogenase

Synonyms:

DMGDHD; ME2GLYDH

SwissProt:

Q9UI17

ELISA Recommended dilution:

5000-10000

WB Predicted band size:

97 kDa

WB Positive control:

Human fetal liver tissue lysate

WB Recommended dilution:

500-2000