小鼠抗FBXO6单克隆抗体

Background:

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class, and its C-terminal region is highly similar to that of rat NFB42 (neural F Box 42 kDa) which may be involved in the control of the cell cycle.

Applications:

WB

Name of antibody:

FBXO6

Immunogen:

Fusion protein of human FBXO6

Full name:

F-box protein 6

Synonyms:

FBG2; FBS2; FBX6; Fbx6b

SwissProt:

Q9NRD1

WB Predicted band size:

34 KD

WB Positive control:

293T, HepG2, K562, Jurkat, MCF7 lysates

WB Recommended dilution:

200-1000