兔抗DLK1多克隆抗体

Background:

This gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth. The encoded protein is involved in the differentiation of several cell types including adipocytes. This gene is located in a region of chromosome 14 frequently showing unparental disomy, and is imprinted and expressed from the paternal allele. A single nucleotide variant in this gene is associated with child and adolescent obesity and shows polar overdominance, where heterozygotes carrying an active paternal allele express the phenotype, while mutant homozygotes are normal.

Applications:

ELISA, WB, IHC

Name of antibody:

DLK1

Immunogen:

Fusion protein of human DLK1

Full name:

delta like non-canonical Notch ligand 1

Synonyms:

DLK; FA1; ZOG; pG2; DLK-1; PREF1; Delta1; Pref-1

SwissProt:

P80370

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human colorectal cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

41 kDa

WB Positive control:

HEPG2 and 231 cell lysates

WB Recommended dilution:

500-2000