兔抗HDAC3(Phospho-Ser424) 多克隆抗体

Background:

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1.

Applications:

WB

Name of antibody:

HDAC3(Phospho-Ser424)

Immunogen:

Peptide sequence around phosphorylation site of Serine 424 (K-E-S(p)-D-V) derived from Human HDAC3

Full name:

histone deacetylase 3

Synonyms：

HD3; RPD3; RPD3-2

SwissProt:

O15379

WB Predicted band size:

49 kDa

WB Positive control:

Mouse brain tissue lysates

WB Recommended dilution:

500-1000