兔抗ALOX15多克隆抗体

Background:

Arachidonate 15-lipoxygenase is an enzyme that in humans is encoded by the ALOX15 gene. Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid into 12-hydroperoxyeicosatetraenoic acid/12-HPETE and 15-hydroperoxyeicosatetraenoic acid/15-HPETE. Also converts linoleic acid to 13-hydroperoxyoctadecadienoic acid. May also act on (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE to produce hepoxilin A3.

Applications:

ELISA, IHC

Name of antibody:

ALOX15

Immunogen:

Synthetic peptide of human ALOX15

Full name:

arachidonate 15-lipoxygenase

Synonyms:

12-LOX; L-12LO

SwissProt:

P16050

IHC positive control:

Human gastric cancer and human liver cancer

IHC Recommend dilution:

50-200