兔抗CTSB多克隆抗体

Background:

The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

CTSB

Immunogen:

Fusion protein of human CTSB

Full name:

cathepsin B

Synonyms：

APPS, CPSB

SwissProt:

P07858

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human lung cancer

IHC Recommend dilution:

50-100