兔抗XRCC6多克隆抗体

Background:

The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.

Applications:

ELISA, IHC

Name of antibody:

XRCC6

Immunogen:

Fusion protein of human XRCC6

Full name:

X-ray repair complementing defective repair in Chinese hamster cells 6

Synonyms：

ML8, KU70, TLAA, CTC75, CTCBF, G22P1

SwissProt:

P12956

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human colon cancer and human ovarian cancer

IHC Recommend dilution:

10-50