兔抗CTNNB1(Phospho-Tyr489) 多克隆抗体

Background:

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete.

Applications:

WB

Name of antibody:

CTNNB1(Phospho-Tyr489)

Immunogen:

Peptide sequence around phosphorylation site of Tyrosine 489 (L-H-Y(p)-G-L) derived from Human Catenin- beta.

Full name:

catenin (cadherin-associated protein), beta 1, 88kDa

Synonyms：

CTNNB; MRD19; armadillo

SwissProt:

P35222

WB Predicted band size:

85 kDa

WB Positive control:

Mouse renin lysates

WB Recommended dilution:

500-1000