兔抗COL18A1多克隆抗体

Background:

This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

COL18A1

Immunogen:

Synthetic peptide of human COL18A1

Full name:

collagen, type XVIII, alpha 1

Synonyms：

KS; KNO; KNO1

SwissProt:

P39060

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human prostate cancer and Human brain

IHC Recommend dilution:

100-300