小鼠抗SIRT6单克隆抗体

Background:

This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms.

Applications:

WB, IF, IP

Name of antibody:

SIRT6

Immunogen:

Fusion protein of human SIRT6

Full name:

sirtuin 6

Synonyms:

SIR2L6

SwissProt:

Q8N6T7

WB Predicted band size:

39 kDa

WB Positive control:

Jurkat, MCF7, HCT116, K562, COS7, C2C12, 3T3 and Hela cell lysates

WB Recommended dilution:

500-2000

IF positive control:

Hela cells