兔抗LRPAP1多克隆抗体

Background:

Low density lipoprotein receptor-related protein associated protein 1 also known as LRPAP1 or RAP is a chaperone protein which in humans is encoded by the LRPAP1 gene. LRPAP1 is involved with trafficking of certain members of the LDL receptor family including LRP1 and LRP2. It is a glycoprotein that binds to the alpha-2-macroglobulin receptor, as well as to other members of the low density lipoprotein receptor family. It acts to inhibit the binding of all know ligands for these receptors, and may prevent receptor aggregation and degradation in the endoplasmic reticulum, thereby acting as a molecular chaperone. It may be under the regulatory control of calmodulin, since it is able to bind calmodulin and be phosphorylated by calmodulin-dependent kinase II.

Applications:

ELISA, WB, IHC

Name of antibody:

LRPAP1

Immunogen:

Synthetic peptide of human LRPAP1

Full name:

low density lipoprotein receptor-related protein associated protein 1

Synonyms：

RAP, MRAP, A2RAP, HBP44, A2MRAP

SwissProt:

P30533

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human colon cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

41 kDa

WB Positive control:

293T cells and fetal kidney tissue

WB Recommended dilution:

500-2000