兔抗CHUK(Phospho-Ser180/181) 多克隆抗体

Background:

This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.

Applications:

WB

Name of antibody:

CHUK(Phospho-Ser180/181)

Immunogen:

Peptide sequence around phosphorylation site of serine 180/181 (C-T-S(p)-F-V) derived from Human IKK- alpha/ beta.

Full name:

conserved helix-loop-helix ubiquitous kinase

Synonyms：

IKK1; IKKA; IKBKA; TCF16; NFKBIKA; IKK-alpha

SwissProt:

O15111

WB Predicted band size:

85 kDa

WB Positive control:

HepG2 cells lysates treated with TNF

WB Recommended dilution:

500-1000