兔抗CHP2多克隆抗体

Background:

This gene product is a small calcium-binding protein that regulates cell pH by controlling plasma membrane-type Na+/H+ exchange activity. This protein shares sequence similarity with calcineurin B and can bind to and stimulate the protein phosphatase activity of calcineurin A (CnA) and functions in the calcineurin/NFAT (nuclear factor of activated T cells) signaling pathway. Another member of the CHP subfamily, Calcineurin B homologous protein 1, is located on Chromosome 15 and is an inhibitor of calcineurin activity and has a genetic phenotype associated with Parkinson's Disease (OMIM:606988). This gene was initially identified as a tumor-associated antigen and was previously referred to as Hepatocellular carcinoma-associated antigen 520.

Applications:

WB

Name of antibody:

CHP2

Immunogen:

Synthesized peptide derived from internal of humanCHP2.

Full name:

calcineurin-like EF-hand protein 2

Synonyms：

0

SwissProt:

O43745

WB Predicted band size:

22 kDa

WB Positive control:

Jurkat cells, K562 cells and HT-29 cells lysates

WB Recommended dilution:

500-3000