小鼠抗PRMT1单克隆抗体

Background:

This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5.

Applications:

WB

Name of antibody:

PRMT1

Immunogen:

Fusion protein of human PRMT1

Full name:

protein arginine methyltransferase 1

Synonyms:

ANM1; HCP1; IR1B4; HRMT1L2

SwissProt:

Q99873

WB Predicted band size:

42 kDa

WB Positive control:

SW480, Hela and A549 cell lysates

WB Recommended dilution:

1000-5000