兔抗COMP多克隆抗体

Background:

The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).

Applications:

ELISA, IHC

Name of antibody:

COMP

Immunogen:

Fusion protein of human COMP

Full name:

cartilage oligomeric matrix protein

Synonyms：

MED; EDM1; EPD1; PSACH; THBS5

SwissProt:

P49747

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human thyroid cancer and Human breast cancer

IHC Recommend dilution:

100-300