兔抗ELAVL1多克隆抗体

Background:

The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy.

Applications:

ELISA, WB, IHC

Name of antibody:

ELAVL1

Immunogen:

Fusion protein of human ELAVL1

Full name:

ELAV like RNA binding protein 1

Synonyms：

HUR; Hua; MelG; ELAV1

SwissProt:

Q15717

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human lung cancer and human brain

IHC Recommend dilution:

50-200

WB Predicted band size:

36 kDa

WB Positive control:

293T, A431, NIH/3T3, hela and hepG2 cells

WB Recommended dilution:

500-2000