兔抗KLRC3多克隆抗体

Background:

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC3 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. Alternative splicing results in multiple transcript variants encoding different isoforms.

Applications:

ELISA, IHC

Name of antibody:

KLRC3

Immunogen:

Synthetic peptide of human KLRC3

Full name:

killer cell lectin-like receptor subfamily C, member 3

Synonyms：

NKG2E; NKG2-E

SwissProt:

Q07444

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil and human cervical cancer

IHC Recommend dilution:

25-100