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Background: |
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC3 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. Alternative splicing results in multiple transcript variants encoding different isoforms. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
KLRC3 |
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Immunogen: |
Synthetic peptide of human KLRC3 |
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Full name: |
killer cell lectin-like receptor subfamily C, member 3 |
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Synonyms： |
NKG2E; NKG2-E |
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SwissProt: |
Q07444 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human tonsil and human cervical cancer |
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IHC Recommend dilution: |
25-100 |
