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021-54845833/15800441009
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Background: |
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq]. |
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Applications: |
WB, IHC, IF, FC |
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Name of antibody: |
SIRT5 |
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Immunogen: |
Fusion protein of human SIRT5 |
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Full name: |
sirtuin 5 (SIRT5), transcript variant 1 |
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Synonyms: |
SIR2L5 |
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SwissProt: |
Q9NXA8 |
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IHC positive control: |
human kidney tissue |
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IHC Recommend dilution: |
30-150 |
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WB Predicted band size: |
34 kDa |
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WB Positive control: |
HepG2, Hela, COS7, PC12, MCF-7 cell lysates |
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WB Recommended dilution: |
200-1000 |
