小鼠抗SIRT5单克隆抗体

Background:

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq].

Applications:

WB, IHC, IF, FC

Name of antibody:

SIRT5

Immunogen:

Fusion protein of human SIRT5

Full name:

sirtuin 5 (SIRT5), transcript variant 1

Synonyms:

SIR2L5

SwissProt:

Q9NXA8

IHC positive control:

human kidney tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

34 kDa

WB Positive control:

HepG2, Hela, COS7, PC12, MCF-7 cell lysates

WB Recommended dilution:

200-1000