兔抗SOCS6多克隆抗体

Background:

The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.

Applications:

ELISA, WB, IHC

Name of antibody:

SOCS6

Immunogen:

Fusion protein of human SOCS6

Full name:

suppressor of cytokine signaling 6

Synonyms:

CIS4; SSI4; CIS-4; SOCS4; STAI4; SOCS-4; SOCS-6; STATI4; HSPC060

SwissProt:

O14544

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

60 kDa

WB Positive control:

Human placenta tissue lysate

WB Recommended dilution:

200-1000