兔抗LIN37多克隆抗体

Background:

The LIN proteins regulate an intercellular signaling process that induces formation of the hermaphrodite vulva in C. elegans by acting to prevent the activation of a receptor tyrosine kinase/Ras signaling pathway. LIN37 is a 246 amino acid protein that is a mammalian homolog of the C. elegans Lin-37 protein. LIN37 functions as a component of the DREAM complex (also known as the LINC complex), which is comprised of several proteins, all of which work in concert to repress cell cycle-dependent genes. LIN37 is encoded by a gene located on human chromosome 19q13.2.

Applications:

ELISA, IHC

Name of antibody:

LIN37

Immunogen:

Fusion protein of human LIN37

Full name:

lin-37 DREAM MuvB core complex component

Synonyms:

F25965; lin-37; ZK418.4

SwissProt:

Q96GY3

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human prostate cancer and Human liver cancer

IHC Recommend dilution:

50-200