兔抗KMT2B多克隆抗体

Background:

This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known.

Applications:

ELISA, IHC

Name of antibody:

KMT2B

Immunogen:

Synthetic peptide of human KMT2B

Full name:

lysine (K)-specific methyltransferase 2B

Synonyms：

HRX2; MLL2; MLL4; TRX2; WBP7; MLL1B; WBP-7; CXXC10

SwissProt:

Q9UMN6

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human gastric cancer and human lung cancer

IHC Recommend dilution:

25-100