兔抗KLK5多克隆抗体

Background:

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein.

Applications:

ELISA, WB, IHC

Name of antibody:

KLK5

Immunogen:

Synthetic peptide of human KLK5

Full name:

kallikrein-related peptidase 5

Synonyms：

SCTE, KLKL2, KLK-L2

SwissProt:

Q9Y337

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human ovarian cancer

IHC Recommend dilution:

100-300

WB Predicted band size:

32 kDa

WB Positive control:

Mouse brain tissue

WB Recommended dilution:

1000-5000