兔抗ITGAE多克隆抗体

Background:

Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation.

Applications:

ELISA, IHC

Name of antibody:

ITGAE

Immunogen:

Fusion protein of human ITGAE

Full name:

integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)

Synonyms：

CD103; HUMINAE

SwissProt:

P38570

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human colon cancer and Human lung cancer

IHC Recommend dilution:

50-200