兔抗SLC17A1多克隆抗体

Background:

NPT1, also called sodium-dependent phosphate transport protein, belongs to the organic anion transporter family, SLC17A. It is mainly expressed in the kidney transporting small organic anions such as PAH (para-aminohippurate), but it is also found in the liver and brain. NTP1 localizes to the apical membrane of renal proximal tubular cells and functions as a voltage driven organic anion/Cl-exchanger. It also plays a role in maintaining phosphate homeostasis. The expression of NPT1 is transcriptionally regulated by HNF-1 and HNF-3∫. Indomethacin and salicylate inhibit NPT1-mediated PAH transport.

Applications:

ELISA, WB

Name of antibody:

SLC17A1

Immunogen:

Synthetic peptide of human SLC17A1

Full name:

solute carrier family 17 (organic anion transporter), member 1

Synonyms：

NPT1; NPT-1; NAPI-1

SwissProt:

Q14916

ELISA Recommended dilution:

2000-5000

WB Predicted band size:

51 kDa

WB Positive control:

Human kidney pericarcinous and kidney cancer tissue

WB Recommended dilution:

500-2000